Newly downloaded neuroimading data are placed in the queue for the MR and PET imaging nuclei, where they are subject to a quality assessment. Isolated data is provided to the MR and PET nuclei via an applet that downloads all scans into the queue. Once the quality assessment is complete, the results are returned to the repository, usually within a few days of the acquisition. When the results of the quality assessment are received, images that receive a successful evaluation are automatically removed from quarantine, with the status “available” and are immediately available to DNAI investigators. Images that do not receive a successful rating are granted non-status status and are still unavailable. The MR and PET image nuclei also generate corrected pre-processed images that are uploaded daily to the repository. Pre-processed images are only generated for images that have passed a quality assessment [8-9]. Basic image analysts MR and PET draw pre-processed images from the repository and provide quarterly analysis results that are also integrated into the repository and shared with ADNI users.
The computer core has developed standards and methods for collecting neuroimaging data (processes that have gone through an image) and for covering image analysis methods. Collecting information and methods of transmitting images allows external auditors to understand how the processed data was generated  and how it is associated with primary data, both important aspects of data reuse and replication. In addition, provenance metadata is useful as search criteria for those who search for processed images for their search. The lack of standardized data formats and descriptors often hinders the exchange and integration of neuroscience data , but file format translators embedded in the ADNI archive allow investigators to download images into a number of common file formats. After ten years, the computer core of ADNI has learned a number of lessons.